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Structural insights into mode of actions of novel natural Mycobacterium protein tyrosine phosphatase B inhibitors
BACKGROUND: Tuberculosis has become a major health problem being the second leading cause of death worldwide. Mycobacterium tuberculosis secretes a virulence factor, protein tyrosine phosphatase B (mPTPB) in the cytoplasm of host macrophage which suppresses its natural innate immune response and hel...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046716/ https://www.ncbi.nlm.nih.gov/pubmed/24564493 http://dx.doi.org/10.1186/1471-2164-15-S1-S3 |