Biodegradable Polymeric Nanoparticles Show High Efficacy and Specificity at DNA Delivery to Human Glioblastoma in Vitro and in Vivo

[Image: see text] Current glioblastoma therapies are insufficient to prevent tumor recurrence and eventual death. Here, we describe a method to treat malignant glioma by nonviral DNA delivery using biodegradable poly(β-amino ester)s (PBAEs), with a focus on the brain tumor initiating cells (BTICs),...

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Detalles Bibliográficos
Autores principales: Guerrero-Cázares, Hugo, Tzeng, Stephany Y., Young, Noah P., Abutaleb, Ameer O., Quiñones-Hinojosa, Alfredo, Green, Jordan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046784/
https://www.ncbi.nlm.nih.gov/pubmed/24766032
http://dx.doi.org/10.1021/nn501197v

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046784/
https://www.ncbi.nlm.nih.gov/pubmed/24766032
http://dx.doi.org/10.1021/nn501197v

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