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Yeast Synthetic Biology Platform Generates Novel Chemical Structures as Scaffolds for Drug Discovery

[Image: see text] Synthetic biology has been heralded as a new bioengineering platform for the production of bulk and specialty chemicals, drugs, and fuels. Here, we report for the first time a series of 74 novel compounds produced using a combinatorial genetics approach in baker’s yeast. Based on t...

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Detalles Bibliográficos
Autores principales: Klein, Jens, Heal, Jonathan R., Hamilton, William D. O., Boussemghoune, Thiamo, Tange, Thomas Østergaard, Delegrange, Fanny, Jaeschke, Georg, Hatsch, Anaëlle, Heim, Jutta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046787/
https://www.ncbi.nlm.nih.gov/pubmed/24742115
http://dx.doi.org/10.1021/sb400177x