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Selective Uptake and Imaging of Aptamer- and Antibody-Conjugated Hollow Nanospheres Targeted to Epidermal Growth Factor Receptors Overexpressed in Head and Neck Cancer

[Image: see text] The purpose of this study was to compare the binding affinity and selective targeting of aptamer- and antibody-coated hollow gold nanospheres (HAuNS) targeted to epidermal growth factor receptors (EGFR). EGFR-targeting aptamers were conjugated to HAuNS (apt-HAuNS) by attaching a th...

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Detalles Bibliográficos
Autores principales: Melancon, Marites Pasuelo, Zhou, Min, Zhang, Rui, Xiong, Chiyi, Allen, Peter, Wen, Xiaoxia, Huang, Qian, Wallace, Michael, Myers, Jeffrey N., Stafford, R. Jason, Liang, Dong, Ellington, Andrew D., Li, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046795/
https://www.ncbi.nlm.nih.gov/pubmed/24754567
http://dx.doi.org/10.1021/nn406632u