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An improved ChIP-seq peak detection system for simultaneously identifying post-translational modified transcription factors by combinatorial fusion, using SUMOylation as an example

BACKGROUND: Post-translational modification (PTM) of transcriptional factors and chromatin remodelling proteins is recognized as a major mechanism by which transcriptional regulation occurs. Chromatin immunoprecipitation (ChIP) in combination with high-throughput sequencing (ChIP-seq) is being appli...

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Detalles Bibliográficos
Autores principales: Cheng, Chia-Yang, Chu, Chia-Han, Hsu, Hung-Wei, Hsu, Fang-Rong, Tang, Chung Yi, Wang, Wen-Ching, Kung, Hsing-Jien, Chang, Pei-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046823/
https://www.ncbi.nlm.nih.gov/pubmed/24564277
http://dx.doi.org/10.1186/1471-2164-15-S1-S1