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Integrated Pathway-Based Approach Identifies Association between Genomic Regions at CTCF and CACNB2 and Schizophrenia

In the present study, an integrated hierarchical approach was applied to: (1) identify pathways associated with susceptibility to schizophrenia; (2) detect genes that may be potentially affected in these pathways since they contain an associated polymorphism; and (3) annotate the functional conseque...

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Detalles Bibliográficos
Autores principales: Juraeva, Dilafruz, Haenisch, Britta, Zapatka, Marc, Frank, Josef, Witt, Stephanie H., Mühleisen, Thomas W., Treutlein, Jens, Strohmaier, Jana, Meier, Sandra, Degenhardt, Franziska, Giegling, Ina, Ripke, Stephan, Leber, Markus, Lange, Christoph, Schulze, Thomas G., Mössner, Rainald, Nenadic, Igor, Sauer, Heinrich, Rujescu, Dan, Maier, Wolfgang, Børglum, Anders, Ophoff, Roel, Cichon, Sven, Nöthen, Markus M., Rietschel, Marcella, Mattheisen, Manuel, Brors, Benedikt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046913/
https://www.ncbi.nlm.nih.gov/pubmed/24901509
http://dx.doi.org/10.1371/journal.pgen.1004345