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Integrated Pathway-Based Approach Identifies Association between Genomic Regions at CTCF and CACNB2 and Schizophrenia
In the present study, an integrated hierarchical approach was applied to: (1) identify pathways associated with susceptibility to schizophrenia; (2) detect genes that may be potentially affected in these pathways since they contain an associated polymorphism; and (3) annotate the functional conseque...
Autores principales: | Juraeva, Dilafruz, Haenisch, Britta, Zapatka, Marc, Frank, Josef, Witt, Stephanie H., Mühleisen, Thomas W., Treutlein, Jens, Strohmaier, Jana, Meier, Sandra, Degenhardt, Franziska, Giegling, Ina, Ripke, Stephan, Leber, Markus, Lange, Christoph, Schulze, Thomas G., Mössner, Rainald, Nenadic, Igor, Sauer, Heinrich, Rujescu, Dan, Maier, Wolfgang, Børglum, Anders, Ophoff, Roel, Cichon, Sven, Nöthen, Markus M., Rietschel, Marcella, Mattheisen, Manuel, Brors, Benedikt |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046913/ https://www.ncbi.nlm.nih.gov/pubmed/24901509 http://dx.doi.org/10.1371/journal.pgen.1004345 |
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