AprioriGWAS, a New Pattern Mining Strategy for Detecting Genetic Variants Associated with Disease through Interaction Effects

Identifying gene-gene interaction is a hot topic in genome wide association studies. Two fundamental challenges are: (1) how to smartly identify combinations of variants that may be associated with the trait from astronomical number of all possible combinations; and (2) how to test epistatic interac...

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Detalles Bibliográficos
Autores principales: Zhang, Qingrun, Long, Quan, Ott, Jurg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046917/
https://www.ncbi.nlm.nih.gov/pubmed/24901472
http://dx.doi.org/10.1371/journal.pcbi.1003627

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046917/
https://www.ncbi.nlm.nih.gov/pubmed/24901472
http://dx.doi.org/10.1371/journal.pcbi.1003627

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