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Coiled-Coil Proteins Facilitated the Functional Expansion of the Centrosome

Repurposing existing proteins for new cellular functions is recognized as a main mechanism of evolutionary innovation, but its role in organelle evolution is unclear. Here, we explore the mechanisms that led to the evolution of the centrosome, an ancestral eukaryotic organelle that expanded its func...

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Detalles Bibliográficos
Autores principales: Kuhn, Michael, Hyman, Anthony A., Beyer, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046923/
https://www.ncbi.nlm.nih.gov/pubmed/24901223
http://dx.doi.org/10.1371/journal.pcbi.1003657