Structural Insight into the Tetramerization of an Iterative Ketoreductase SiaM through Aromatic Residues in the Interfaces

In the biosynthesis of polyketides, ketoreductases (KRs) are an important group of enzymes that determine the chiralities of the carbon backbones. SiaM is a special member of this group that can recognize substrates with different lengths and can be used iteratively. Here we report the crystal struc...

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Detalles Bibliográficos
Autores principales: Wang, Hua, Zhang, Huaidong, Zou, Yi, Mi, Yanling, Lin, Shuangjun, Xie, Zhixiong, Yan, Yunjun, Zhang, Houjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046962/
https://www.ncbi.nlm.nih.gov/pubmed/24901639
http://dx.doi.org/10.1371/journal.pone.0097996

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046962/
https://www.ncbi.nlm.nih.gov/pubmed/24901639
http://dx.doi.org/10.1371/journal.pone.0097996

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