Induction of Cell-Mediated Immune Responses in Mice by DNA Vaccines That Express Hepatitis C Virus NS3 Mutants Lacking Serine Protease and NTPase/RNA Helicase Activities

Effective therapeutic vaccines against virus infection must induce sufficient levels of cell-mediated immune responses against the target viral epitopes and also must avoid concomitant risk factors, such as potential carcinogenic properties. The nonstructural protein 3 (NS3) of hepatitis C virus (HC...

Descripción completa

Detalles Bibliográficos
Autores principales: Ratnoglik, Suratno Lulut, Jiang, Da-Peng, Aoki, Chie, Sudarmono, Pratiwi, Shoji, Ikuo, Deng, Lin, Hotta, Hak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046998/
https://www.ncbi.nlm.nih.gov/pubmed/24901478
http://dx.doi.org/10.1371/journal.pone.0098877

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046998/
https://www.ncbi.nlm.nih.gov/pubmed/24901478
http://dx.doi.org/10.1371/journal.pone.0098877

Ejemplares similares