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Functional properties of the HIV-1 long terminal repeat containing single-nucleotide polymorphisms in Sp site III and CCAAT/enhancer binding protein site I

BACKGROUND: HIV-1 gene expression is driven by the long terminal repeat (LTR), which contains many binding sites shown to interact with an array of host and viral factors. Selective pressures within the host as well as the low fidelity of reverse transcriptase lead to changes in the relative prevale...

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Detalles Bibliográficos
Autores principales: Shah, Sonia, Alexaki, Aikaterini, Pirrone, Vanessa, Dahiya, Satinder, Nonnemacher, Michael R, Wigdahl, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047001/
https://www.ncbi.nlm.nih.gov/pubmed/24886416
http://dx.doi.org/10.1186/1743-422X-11-92