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Oxidative Stress Decreases Functional Airway Mannose Binding Lectin in COPD

We have previously established that a defect in the ability of alveolar macrophages (AM) to phagocytose apoptotic cells (efferocytosis) and pathogens is a potential therapeutic target in COPD. We further showed that levels of mannose binding lectin (MBL; required for effective macrophage phagocytic...

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Detalles Bibliográficos
Autores principales: Tran, Hai B., Ahern, Jessica, Hodge, Greg, Holt, Phillip, Dean, Melinda M., Reynolds, Paul N., Hodge, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047017/
https://www.ncbi.nlm.nih.gov/pubmed/24901869
http://dx.doi.org/10.1371/journal.pone.0098571