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A Genetically-Encoded YFP Sensor with Enhanced Chloride Sensitivity, Photostability and Reduced pH Interference Demonstrates Augmented Transmembrane Chloride Movement by Gerbil Prestin (SLC26a5)

BACKGROUND: Chloride is the major anion in cells, with many diseases arising from disordered Cl(−) regulation. For the non-invasive investigation of Cl(−) flux, YFP-H148Q and its derivatives chameleon and Cl-Sensor previously were introduced as genetically encoded chloride indicators. Neither the Cl...

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Detalles Bibliográficos
Autores principales: Zhong, Sheng, Navaratnam, Dhasakumar, Santos-Sacchi, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047046/
https://www.ncbi.nlm.nih.gov/pubmed/24901231
http://dx.doi.org/10.1371/journal.pone.0099095