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A Genetically-Encoded YFP Sensor with Enhanced Chloride Sensitivity, Photostability and Reduced pH Interference Demonstrates Augmented Transmembrane Chloride Movement by Gerbil Prestin (SLC26a5)
BACKGROUND: Chloride is the major anion in cells, with many diseases arising from disordered Cl(−) regulation. For the non-invasive investigation of Cl(−) flux, YFP-H148Q and its derivatives chameleon and Cl-Sensor previously were introduced as genetically encoded chloride indicators. Neither the Cl...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047046/ https://www.ncbi.nlm.nih.gov/pubmed/24901231 http://dx.doi.org/10.1371/journal.pone.0099095 |