Cargando…

Acute Sterol O-Acyltransferase 2 (SOAT2) Knockdown Rapidly Mobilizes Hepatic Cholesterol for Fecal Excretion

The primary risk factor for atherosclerotic cardiovascular disease is LDL cholesterol, which can be reduced by increasing cholesterol excretion from the body. Fecal cholesterol excretion can be driven by a hepatobiliary as well as a non-biliary pathway known as transintestinal cholesterol efflux (TI...

Descripción completa

Detalles Bibliográficos
Autores principales: Marshall, Stephanie M., Gromovsky, Anthony D., Kelley, Kathryn L., Davis, Matthew A., Wilson, Martha D., Lee, Richard G., Crooke, Rosanne M., Graham, Mark J., Rudel, Lawrence L., Brown, J. Mark, Temel, Ryan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047063/
https://www.ncbi.nlm.nih.gov/pubmed/24901470
http://dx.doi.org/10.1371/journal.pone.0098953