Activation of Focal Adhesion Kinase by Salmonella Suppresses Autophagy via an Akt/mTOR Signaling Pathway and Promotes Bacterial Survival in Macrophages

Autophagy has emerged as an important antimicrobial host defense mechanism that not only orchestrates the systemic immune response, but also functions in a cell autonomous manner to directly eliminate invading pathogens. Pathogenic bacteria such as Salmonella have evolved adaptations to protect them...

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Detalles Bibliográficos
Autores principales: Owen, Katherine A., Meyer, Corey B., Bouton, Amy H., Casanova, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047085/
https://www.ncbi.nlm.nih.gov/pubmed/24901456
http://dx.doi.org/10.1371/journal.ppat.1004159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047085/
https://www.ncbi.nlm.nih.gov/pubmed/24901456
http://dx.doi.org/10.1371/journal.ppat.1004159

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