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Heat-Shock Protein 90 Promotes Nuclear Transport of Herpes Simplex Virus 1 Capsid Protein by Interacting with Acetylated Tubulin

Although it is known that inhibitors of heat shock protein 90 (Hsp90) can inhibit herpes simplex virus type 1 (HSV-1) infection, the role of Hsp90 in HSV-1 entry and the antiviral mechanisms of Hsp90 inhibitors remain unclear. In this study, we found that Hsp90 inhibitors have potent antiviral activ...

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Detalles Bibliográficos
Autores principales: Zhong, Meigong, Zheng, Kai, Chen, Maoyun, Xiang, Yangfei, Jin, Fujun, Ma, Kaiqi, Qiu, Xianxiu, Wang, Qiaoli, Peng, Tao, Kitazato, Kaio, Wang, Yifei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047101/
https://www.ncbi.nlm.nih.gov/pubmed/24901434
http://dx.doi.org/10.1371/journal.pone.0099425