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Tumor Suppressor DYRK1A Effects on Proliferation and Chemoresistance of AML Cells by Downregulating c-Myc

Acute myeloid leukemia (AML), caused by abnormal proliferation and accumulation of hematopoietic progenitor cells, is one of the most common malignancies in adults. We reported here DYRK1A expression level was reduced in the bone marrow of adult AML patients, comparing to normal controls. Overexpres...

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Detalles Bibliográficos
Autores principales: Liu, Qiang, Liu, Na, Zang, Shaolei, Liu, Heng, Wang, Pin, Ji, Chunyan, Sun, Xiulian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047119/
https://www.ncbi.nlm.nih.gov/pubmed/24901999
http://dx.doi.org/10.1371/journal.pone.0098853