Cargando…
Tumor Suppressor DYRK1A Effects on Proliferation and Chemoresistance of AML Cells by Downregulating c-Myc
Acute myeloid leukemia (AML), caused by abnormal proliferation and accumulation of hematopoietic progenitor cells, is one of the most common malignancies in adults. We reported here DYRK1A expression level was reduced in the bone marrow of adult AML patients, comparing to normal controls. Overexpres...
Autores principales: | Liu, Qiang, Liu, Na, Zang, Shaolei, Liu, Heng, Wang, Pin, Ji, Chunyan, Sun, Xiulian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047119/ https://www.ncbi.nlm.nih.gov/pubmed/24901999 http://dx.doi.org/10.1371/journal.pone.0098853 |
Ejemplares similares
-
Novel Agent Nitidine Chloride Induces Erythroid Differentiation and Apoptosis in CML Cells through c-Myc-miRNAs Axis
por: Liu, Na, et al.
Publicado: (2015) -
DYRK2 downregulation in colorectal cancer leads to epithelial–mesenchymal transition induction and chemoresistance
por: Wu, Chunrong, et al.
Publicado: (2022) -
E3 Ligase SCF(βTrCP)-induced DYRK1A Protein Degradation Is Essential for Cell Cycle Progression in HEK293 Cells
por: Liu, Qiang, et al.
Publicado: (2016) -
Wnt signaling is involved in 6-benzylthioinosine-induced AML cell differentiation
por: Zang, Shaolei, et al.
Publicado: (2014) -
DYRK1A phosphorylates MEF2D and decreases its transcriptional activity
por: Wang, Pin, et al.
Publicado: (2021)