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A comparative study of experimental mouse models of central nervous system demyelination

Several mouse models of multiple sclerosis (MS) are now available. We have established a mouse model, in which ocular infection with a recombinant HSV-1 that expresses murine IL-2 constitutively (HSV-IL-2) causes CNS demyelination in different strains of mice. This model differs from most other mode...

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Detalles Bibliográficos
Autores principales: Dumitrascu, Oana M., Mott, Kevin R., Ghiasi, Homayon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047154/
https://www.ncbi.nlm.nih.gov/pubmed/24718267
http://dx.doi.org/10.1038/gt.2014.33