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A comparative study of experimental mouse models of central nervous system demyelination
Several mouse models of multiple sclerosis (MS) are now available. We have established a mouse model, in which ocular infection with a recombinant HSV-1 that expresses murine IL-2 constitutively (HSV-IL-2) causes CNS demyelination in different strains of mice. This model differs from most other mode...
Autores principales: | Dumitrascu, Oana M., Mott, Kevin R., Ghiasi, Homayon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047154/ https://www.ncbi.nlm.nih.gov/pubmed/24718267 http://dx.doi.org/10.1038/gt.2014.33 |
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