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rAAV9 combined with renal vein injection is optimal for kidney-targeted gene delivery: conclusion of a comparative study

Effective gene therapy strategies for the treatment of kidney disorders remain elusive. We report an optimized kidney-targeted gene delivery strategy using recombinant Adeno-Associated Viruses (rAAV) administered via retrograde renal vein injection in mice. Renal vein injection of rAAV consistently...

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Detalles Bibliográficos
Autores principales: Rocca, Céline J., Ur, Sarah N., Harrison, Frank, Cherqui, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047163/
https://www.ncbi.nlm.nih.gov/pubmed/24784447
http://dx.doi.org/10.1038/gt.2014.35