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rAAV9 combined with renal vein injection is optimal for kidney-targeted gene delivery: conclusion of a comparative study
Effective gene therapy strategies for the treatment of kidney disorders remain elusive. We report an optimized kidney-targeted gene delivery strategy using recombinant Adeno-Associated Viruses (rAAV) administered via retrograde renal vein injection in mice. Renal vein injection of rAAV consistently...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047163/ https://www.ncbi.nlm.nih.gov/pubmed/24784447 http://dx.doi.org/10.1038/gt.2014.35 |