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Assembly of the Respiratory Mucin MUC5B: A NEW MODEL FOR A GEL-FORMING MUCIN

Mucins are essential components in mucus gels that form protective barriers at all epithelial surfaces, but much remains unknown about their assembly, intragranular organization, and post-secretion unfurling to form mucus. MUC5B is a major polymeric mucin expressed by respiratory epithelia, and we i...

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Detalles Bibliográficos
Autores principales: Ridley, Caroline, Kouvatsos, Nikos, Raynal, Bertrand D., Howard, Marj, Collins, Richard F., Desseyn, Jean-Luc, Jowitt, Thomas A., Baldock, Clair, Davis, C. William, Hardingham, Timothy E., Thornton, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047408/
https://www.ncbi.nlm.nih.gov/pubmed/24778189
http://dx.doi.org/10.1074/jbc.M114.566679