Quantitative Chemical Proteomics Identifies Novel Targets of the Anti-cancer Multi-kinase Inhibitor E-3810

Novel drugs are designed against specific molecular targets, but almost unavoidably they bind non-targets, which can cause additional biological effects that may result in increased activity or, more frequently, undesired toxicity. Chemical proteomics is an ideal approach for the systematic identifi...

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Detalles Bibliográficos
Autores principales: Colzani, Mara, Noberini, Roberta, Romanenghi, Mauro, Colella, Gennaro, Pasi, Maurizio, Fancelli, Daniele, Varasi, Mario, Minucci, Saverio, Bonaldi, Tiziana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047469/
https://www.ncbi.nlm.nih.gov/pubmed/24696502
http://dx.doi.org/10.1074/mcp.M113.034173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047469/
https://www.ncbi.nlm.nih.gov/pubmed/24696502
http://dx.doi.org/10.1074/mcp.M113.034173

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