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Serotonin-prefrontal cortical circuitry in anxiety and depression phenotypes: pivotal role of pre- and post-synaptic 5-HT1A receptor expression

Decreased serotonergic activity has been implicated in anxiety and major depression, and antidepressants directly or indirectly increase the long-term activity of the serotonin system. A key component of serotonin circuitry is the 5-HT1A autoreceptor, which functions as the major somatodendritic aut...

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Detalles Bibliográficos
Autores principales: Albert, Paul R., Vahid-Ansari, Faranak, Luckhart, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047678/
https://www.ncbi.nlm.nih.gov/pubmed/24936175
http://dx.doi.org/10.3389/fnbeh.2014.00199