Disrupting KATP channels diminishes the estrogen-mediated protection in female mutant mice during ischemia-reperfusion

BACKGROUND: Estrogen has been shown to mediate protection in female hearts against ischemia-reperfusion (I-R) stress. Composed by a Kir6.2 pore and an SUR2 regulatory subunit, cardiac ATP-sensitive potassium channels (KATP) remain quiescent under normal physiological conditions but they are activate...

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Detalles Bibliográficos
Autores principales: Gao, Jianjiong, Xu, Dong, Sabat, Grzegorz, Valdivia, Hector, Xu, Wei, Shi, Nian-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047774/
https://www.ncbi.nlm.nih.gov/pubmed/24936167
http://dx.doi.org/10.1186/1559-0275-11-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047774/
https://www.ncbi.nlm.nih.gov/pubmed/24936167
http://dx.doi.org/10.1186/1559-0275-11-19

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