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Disrupting KATP channels diminishes the estrogen-mediated protection in female mutant mice during ischemia-reperfusion
BACKGROUND: Estrogen has been shown to mediate protection in female hearts against ischemia-reperfusion (I-R) stress. Composed by a Kir6.2 pore and an SUR2 regulatory subunit, cardiac ATP-sensitive potassium channels (KATP) remain quiescent under normal physiological conditions but they are activate...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047774/ https://www.ncbi.nlm.nih.gov/pubmed/24936167 http://dx.doi.org/10.1186/1559-0275-11-19 |