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GABA(B) receptor ligands for the treatment of alcohol use disorder: preclinical and clinical evidence

The present paper summarizes the preclinical and clinical studies conducted to define the “anti-alcohol” pharmacological profile of the prototypic GABA(B) receptor agonist, baclofen, and its therapeutic potential for treatment of alcohol use disorder (AUD). Numerous studies have reported baclofen-in...

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Detalles Bibliográficos
Autores principales: Agabio, Roberta, Colombo, Giancarlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047789/
https://www.ncbi.nlm.nih.gov/pubmed/24936171
http://dx.doi.org/10.3389/fnins.2014.00140