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GABA(B) receptor ligands for the treatment of alcohol use disorder: preclinical and clinical evidence
The present paper summarizes the preclinical and clinical studies conducted to define the “anti-alcohol” pharmacological profile of the prototypic GABA(B) receptor agonist, baclofen, and its therapeutic potential for treatment of alcohol use disorder (AUD). Numerous studies have reported baclofen-in...
Autores principales: | Agabio, Roberta, Colombo, Giancarlo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047789/ https://www.ncbi.nlm.nih.gov/pubmed/24936171 http://dx.doi.org/10.3389/fnins.2014.00140 |
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