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Palmdelphin, a novel target of p53 with Ser46 phosphorylation, controls cell death in response to DNA damage
The tumor suppressor gene p53 regulates apoptosis in response to DNA damage. Promoter selectivity of p53 depends on mainly its phosphorylation. Particularly, the phosphorylation at serine-46 of p53 is indispensable in promoting pro-apoptotic genes that are, however, poorly determined. In the current...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047856/ https://www.ncbi.nlm.nih.gov/pubmed/24810057 http://dx.doi.org/10.1038/cddis.2014.176 |