Cargando…

Palmdelphin, a novel target of p53 with Ser46 phosphorylation, controls cell death in response to DNA damage

The tumor suppressor gene p53 regulates apoptosis in response to DNA damage. Promoter selectivity of p53 depends on mainly its phosphorylation. Particularly, the phosphorylation at serine-46 of p53 is indispensable in promoting pro-apoptotic genes that are, however, poorly determined. In the current...

Descripción completa

Detalles Bibliográficos
Autores principales: Dashzeveg, N, Taira, N, Lu, Z-G, Kimura, J, Yoshida, K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047856/
https://www.ncbi.nlm.nih.gov/pubmed/24810057
http://dx.doi.org/10.1038/cddis.2014.176