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Cell-to-cell variability in cell death: can systems biology help us make sense of it all?

One of the most common observations in cell death assays is that not all cells die at the same time, or at the same treatment dose. Here, using the perspective of the systems biology of apoptosis and the context of cancer treatment, we discuss possible sources of this cell-to-cell variability as wel...

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Detalles Bibliográficos
Autores principales: Xia, X, Owen, M S, Lee, R E C, Gaudet, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047886/
https://www.ncbi.nlm.nih.gov/pubmed/24874733
http://dx.doi.org/10.1038/cddis.2014.199