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Mitochondrial dysfunction driven by the LRRK2-mediated pathway is associated with loss of Purkinje cells and motor coordination deficits in diabetic rat model

Diabetic neuropathy develops on a background of hyperglycemia and an entangled metabolic imbalance. There is increasing evidence of central nervous system involvement in diabetic neuropathy and no satisfactory treatment except maintenance of good glycemic control, thereby highlighting the importance...

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Detalles Bibliográficos
Autores principales: Yang, S, Xia, C, Li, S, Du, L, Zhang, L, Hu, Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047887/
https://www.ncbi.nlm.nih.gov/pubmed/24810053
http://dx.doi.org/10.1038/cddis.2014.184