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Osteopontin deficiency aggravates hepatic injury induced by ischemia–reperfusion in mice

Osteopontin (OPN) is a multifunctional protein involved in hepatic steatosis, inflammation, fibrosis and cancer progression. However, its role in hepatic injury induced by ischemia–reperfusion (I–R) has not yet been investigated. We show here that hepatic warm ischemia for 45 min followed by reperfu...

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Detalles Bibliográficos
Autores principales: Patouraux, S, Rousseau, D, Rubio, A, Bonnafous, S, Lavallard, V J, Lauron, J, Saint-Paul, M-C, Bailly-Maitre, B, Tran, A, Crenesse, D, Gual, P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047890/
https://www.ncbi.nlm.nih.gov/pubmed/24810044
http://dx.doi.org/10.1038/cddis.2014.174