Fas-associated factor (Faf1) is a novel CD40 interactor that regulates CD40-induced NF-κB activation via a negative feedback loop

CD40-induced signalling through ligation with its natural ligand (CD40L/CD154) is dependent on recruitment of TRAF molecules to the cytoplasmic domain of the receptor. Here, we applied the yeast two-hybrid system to examine whether other proteins can interact with CD40. Fas-Associated Factor 1(FAF1)...

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Detalles Bibliográficos
Autores principales: Elmetwali, T, Young, L S, Palmer, D H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047894/
https://www.ncbi.nlm.nih.gov/pubmed/24810049
http://dx.doi.org/10.1038/cddis.2014.172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047894/
https://www.ncbi.nlm.nih.gov/pubmed/24810049
http://dx.doi.org/10.1038/cddis.2014.172

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