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HSCARG downregulates NF-κB signaling by interacting with USP7 and inhibiting NEMO ubiquitination

Nuclear factor κB (NF-κB) signaling is a central pathway that participates in a variety of key processes, including immunity, inflammation, cell growth and differentiation. The activity of NF-κB is strictly regulated by a cluster of proteins, and modifications of these proteins either promote or sup...

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Detalles Bibliográficos
Autores principales: Li, T, Guan, J, Li, S, Zhang, X, Zheng, X
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047896/
https://www.ncbi.nlm.nih.gov/pubmed/24832601
http://dx.doi.org/10.1038/cddis.2014.197