FoxO mediates APP-induced AICD-dependent cell death

The amyloid precursor protein (APP) is a broadly expressed transmembrane protein that has a significant role in the pathogenesis of Alzheimer's disease (AD). APP can be cleaved at multiple sites to generate a series of fragments including the amyloid β (Aβ) peptides and APP intracellular domain...

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Detalles Bibliográficos
Autores principales: Wang, X, Wang, Z, Chen, Y, Huang, X, Hu, Y, Zhang, R, Ho, M S, Xue, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047897/
https://www.ncbi.nlm.nih.gov/pubmed/24832605
http://dx.doi.org/10.1038/cddis.2014.196

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047897/
https://www.ncbi.nlm.nih.gov/pubmed/24832605
http://dx.doi.org/10.1038/cddis.2014.196

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