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Serum-dependent processing of late apoptotic cells for enhanced efferocytosis

Binding of the serum protein complement component C1q to the surface of dying cells facilitates their clearance by phagocytes in a process termed efferocytosis. Here, we investigate during which phase of apoptotic cell death progression C1q binding takes place. Purified C1q was found to bind to all...

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Detalles Bibliográficos
Autores principales: Liang, Y Y, Arnold, T, Michlmayr, A, Rainprecht, D, Perticevic, B, Spittler, A, Oehler, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047901/
https://www.ncbi.nlm.nih.gov/pubmed/24874736
http://dx.doi.org/10.1038/cddis.2014.210