Involvement of p38 in signal switching from autophagy to apoptosis via the PERK/eIF2α/ATF4 axis in selenite-treated NB4 cells

Selenite has emerged as an optional chemotherapeutic agent for hematological malignancies. Autophagy and apoptosis are both engaged in selenite-induced cell death. In a previous report, we have identified heat shock protein 90 (Hsp90) as a critical modulator of the balance between autophagy and apop...

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Detalles Bibliográficos
Autores principales: Jiang, Q, Li, F, Shi, K, Wu, P, An, J, Yang, Y, Xu, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047911/
https://www.ncbi.nlm.nih.gov/pubmed/24874742
http://dx.doi.org/10.1038/cddis.2014.200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047911/
https://www.ncbi.nlm.nih.gov/pubmed/24874742
http://dx.doi.org/10.1038/cddis.2014.200

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