The inflammatory molecules IL-1β and HMGB1 can rapidly enhance focal seizure generation in a brain slice model of temporal lobe epilepsy

Epilepsy is a neurological disorder characterized by a hyperexcitable brain tissue and unpredictable seizures, i.e., aberrant firing discharges in large neuronal populations. It is well established that proinflammatory cytokines, in addition to their canonical involvement in the immune response, hav...

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Detalles Bibliográficos
Autores principales: Chiavegato, Angela, Zurolo, Emanuele, Losi, Gabriele, Aronica, Eleonora, Carmignoto, Giorgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047964/
https://www.ncbi.nlm.nih.gov/pubmed/24936172
http://dx.doi.org/10.3389/fncel.2014.00155

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047964/
https://www.ncbi.nlm.nih.gov/pubmed/24936172
http://dx.doi.org/10.3389/fncel.2014.00155

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