Nlrp3 Activation in the Intestinal Epithelium Protects against a Mucosal Pathogen

Polymorphisms in the intracellular pattern recognition receptor gene NLRP3 have been associated with susceptibility to Crohn’s disease, a type of inflammatory bowel disease (IBD). Following tissue damage or infection, NLRP3 triggers the formation of inflammasomes, containing NLRP3, ASC and caspase-1...

Descripción completa

Detalles Bibliográficos
Autores principales: Song-Zhao, George X., Srinivasan, Naren, Pott, Johanna, Baban, Dilair, Frankel, Gad, Maloy, Kevin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048180/
https://www.ncbi.nlm.nih.gov/pubmed/24280937
http://dx.doi.org/10.1038/mi.2013.94

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048180/
https://www.ncbi.nlm.nih.gov/pubmed/24280937
http://dx.doi.org/10.1038/mi.2013.94

Ejemplares similares