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Nlrp3 Activation in the Intestinal Epithelium Protects against a Mucosal Pathogen

Polymorphisms in the intracellular pattern recognition receptor gene NLRP3 have been associated with susceptibility to Crohn’s disease, a type of inflammatory bowel disease (IBD). Following tissue damage or infection, NLRP3 triggers the formation of inflammasomes, containing NLRP3, ASC and caspase-1...

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Detalles Bibliográficos
Autores principales:	Song-Zhao, George X., Srinivasan, Naren, Pott, Johanna, Baban, Dilair, Frankel, Gad, Maloy, Kevin J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048180/ https://www.ncbi.nlm.nih.gov/pubmed/24280937 http://dx.doi.org/10.1038/mi.2013.94

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