CRIF1 Deficiency Induces p66shc-Mediated Oxidative Stress and Endothelial Activation

Mitochondrial dysfunction has been implicated in the pathophysiology of various cardiovascular diseases. CRIF1 is a protein present in the mitochondria associated with large mitoribosomal subunits, and CRIF1 knockdown induces mitochondrial dysfunction and promotes ROS production. p66shc is a redox e...

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Detalles Bibliográficos
Autores principales: Nagar, Harsha, Jung, Saet-byel, Kwon, Sun Kwan, Park, Jung-Bum, Shong, Minho, Song, Hee-Jung, Jeon, Byeong Hwa, Irani, Kaikobad, Kim, Cuk-Seong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048193/
https://www.ncbi.nlm.nih.gov/pubmed/24906005
http://dx.doi.org/10.1371/journal.pone.0098670

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048193/
https://www.ncbi.nlm.nih.gov/pubmed/24906005
http://dx.doi.org/10.1371/journal.pone.0098670

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