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A Study of the Relationship between Serum Bile Acids and Propranolol Pharmacokinetics and Pharmacodynamics in Patients with Liver Cirrhosis and in Healthy Controls

The main objectives of the study were to determine the exposure and bioavailability of oral propranolol and to investigate their associations with serum bile acid concentration in patients with liver cirrhosis and in healthy controls. A further objective was to study the pharmacodynamics of proprano...

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Detalles Bibliográficos
Autores principales: Taegtmeyer, Anne B., Haschke, Manuel, Tchambaz, Lydia, Buylaert, Mirabel, Tschöpl, Martin, Beuers, Ulrich, Drewe, Jürgen, Krähenbühl, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048194/
https://www.ncbi.nlm.nih.gov/pubmed/24906133
http://dx.doi.org/10.1371/journal.pone.0097885