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Low Molecular Weight Procyanidins from Grape Seeds Enhance the Impact of 5-Fluorouracil Chemotherapy on Caco-2 Human Colon Cancer Cells

OBJECTIVE: Grape seed procyanidins (PC) are flavan-3-ol oligomers and polymers known for their biological activity in the gut. Grape seed extract (GSE) have been reported to reduce intestinal injury in a rat model of mucositis. We sought to investigate effects of purified PC fractions differing in m...

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Detalles Bibliográficos
Autores principales: Cheah, Ker Y., Howarth, Gordon S., Bindon, Keren A., Kennedy, James A., Bastian, Susan E. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048230/
https://www.ncbi.nlm.nih.gov/pubmed/24905821
http://dx.doi.org/10.1371/journal.pone.0098921