Cargando…

Low Molecular Weight Procyanidins from Grape Seeds Enhance the Impact of 5-Fluorouracil Chemotherapy on Caco-2 Human Colon Cancer Cells

OBJECTIVE: Grape seed procyanidins (PC) are flavan-3-ol oligomers and polymers known for their biological activity in the gut. Grape seed extract (GSE) have been reported to reduce intestinal injury in a rat model of mucositis. We sought to investigate effects of purified PC fractions differing in m...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cheah, Ker Y., Howarth, Gordon S., Bindon, Keren A., Kennedy, James A., Bastian, Susan E. P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048230/ https://www.ncbi.nlm.nih.gov/pubmed/24905821 http://dx.doi.org/10.1371/journal.pone.0098921

Ejemplares similares

Grape Seed Extract Dose-Responsively Decreases Disease Severity in a Rat Model of Mucositis; Concomitantly Enhancing Chemotherapeutic Effectiveness in Colon Cancer Cells
por: Cheah, Ker Yeaw, et al.
Publicado: (2014)

Grape Seed Procyanidins in Pre- and Mild Hypertension: A Registry Study
por: Belcaro, Gianni, et al.
Publicado: (2013)

Apple Pomace Compositional Data Highlighting the Proportional Contribution of Polymeric Procyanidins
por: Bindon, Keren, et al.
Publicado: (2023)

Protective effects of grape seed procyanidin on isoflurane-induced cognitive impairment in mice
por: Gong, Xiangdan, et al.
Publicado: (2020)

Antiproliferative and Apoptotic Effects Triggered by Grape Seed Extract (GSE) versus Epigallocatechin and Procyanidins on Colon Cancer Cell Lines
por: Dinicola, Simona, et al.
Publicado: (2012)

Grape seed-derived procyanidins alleviate gout pain via NLRP3 inflammasome suppression
por: Liu, Hai-Jiao, et al.
Publicado: (2017)

Procyanidin-Rich Extract from Grape Seeds as a Putative Tool against Helicobacter pylori
por: Silvan, Jose Manuel, et al.
Publicado: (2020)

Evaluation of an Integrated Ultrafiltration/Solid Phase Extraction Process for Purification of Oligomeric Grape Seed Procyanidins
por: Gutierrez-Docio, Alba, et al.
Publicado: (2020)

Protective Effect of Procyanidin-Rich Grape Seed Extract against Gram-Negative Virulence Factors
por: Nicolosi, Roberta Maria, et al.
Publicado: (2023)

Grape seed procyanidin extract against lung cancer: the role of microrna-106b, bioavailability, and bioactivity
por: Xue, Bingye, et al.
Publicado: (2018)

Illumina MiSeq sequencing reveals the effects of grape seed procyanidin on rumen archaeal communities in vitro
por: Zhang, Hua, et al.
Publicado: (2020)

Grape Seed Procyanidin Extract (GSPE) Improves Goat Sperm Quality When Preserved at 4 °C
por: Wen, Fei, et al.
Publicado: (2019)

Effects of grape seed procyanidins on antioxidant function, barrier function, microbial community, and metabolites of cecum in geese
por: Deng, Chao, et al.
Publicado: (2023)

Grape-Seed-Derived Procyanidin Attenuates Chemotherapy-Induced Cognitive Impairment by Suppressing MMP-9 Activity and Related Blood–Brain-Barrier Damage
por: Song, Chao, et al.
Publicado: (2022)

Synergistic Radiation Protective Effect of Purified Auricularia auricular-judae Polysaccharide (AAP IV) with Grape Seed Procyanidins
por: Bai, Haina, et al.
Publicado: (2014)

Antioxidant and Hepatoprotective Effects of Procyanidins from Wild Grape (Vitis amurensis) Seeds in Ethanol-Induced Cells and Rats
por: Bak, Min Ji, et al.
Publicado: (2016)

Chemical and Sensory Impacts of Accentuated Cut Edges (ACE) Grape Must Polyphenol Extraction Technique on Shiraz Wines
por: Kang, Wenyu, et al.
Publicado: (2020)

Grape Seed Procyanidin Extract Improves Insulin Production but Enhances Bax Protein Expression in Cafeteria-Treated Male Rats
por: Cedó, Lídia, et al.
Publicado: (2013)

Grape Seed Procyanidins and Cholestyramine Differentially Alter Bile Acid and Cholesterol Homeostatic Gene Expression in Mouse Intestine and Liver
por: Heidker, Rebecca M., et al.
Publicado: (2016)

The combined anticancer of peanut skin procyanidins and resveratrol to CACO‐2 colorectal cancer cells
por: Wang, Na, et al.
Publicado: (2023)

Anti-Inflammatory Effect of Procyanidins from Wild Grape (Vitis amurensis) Seeds in LPS-Induced RAW 264.7 Cells
por: Bak, Min-Ji, et al.
Publicado: (2013)

Maternal intake of grape seed procyanidins during lactation induces insulin resistance and an adiponectin resistance-like phenotype in rat offspring
por: Caimari, Antoni, et al.
Publicado: (2017)

A Ten-Day Grape Seed Procyanidin Treatment Prevents Certain Ageing Processes in Female Rats over the Long Term
por: Grau-Bové, Carme, et al.
Publicado: (2020)

Grape-Seed Procyanidin Extract (GSPE) Seasonal-Dependent Modulation of Glucose and Lipid Metabolism in the Liver of Healthy F344 Rats
por: Rodríguez, Romina M., et al.
Publicado: (2022)

Proanthocyanidin-Rich Grape Seed Extract Reduces Inflammation and Oxidative Stress and Restores Tight Junction Barrier Function in Caco-2 Colon Cells
por: Nallathambi, Rameshprabu, et al.
Publicado: (2020)

PIMT Prevents the Apoptosis of Endothelial Cells in Response to Glycated Low Density Lipoproteins and Protective Effects of Grape Seed Procyanidin B2
por: Li, Xiao-li, et al.
Publicado: (2013)

Time-of-Day Circadian Modulation of Grape-Seed Procyanidin Extract (GSPE) in Hepatic Mitochondrial Dynamics in Cafeteria-Diet-Induced Obese Rats
por: Rodríguez, Romina M., et al.
Publicado: (2022)

Exploring the nanofiltration mass transfer characteristic and concentrate process of procyanidins from grape juice
por: Li, Cunyu, et al.
Publicado: (2019)

Critical Role of FoxO1 in Granulosa Cell Apoptosis Caused by Oxidative Stress and Protective Effects of Grape Seed Procyanidin B2
por: Zhang, Jia-Qing, et al.
Publicado: (2016)

Grape seed procyanidin B2 promotes the autophagy and apoptosis in colorectal cancer cells via regulating PI3K/Akt signaling pathway
por: Zhang, Ruijuan, et al.
Publicado: (2019)

A Grape Seed Procyanidin Extract Ameliorates Fructose-Induced Hypertriglyceridemia in Rats via Enhanced Fecal Bile Acid and Cholesterol Excretion and Inhibition of Hepatic Lipogenesis
por: Downing, Laura E., et al.
Publicado: (2015)

Grape seed procyanidin B2 promotes the autophagy and apoptosis in colorectal cancer cells via regulating PI3K/Akt signaling pathway [Corrigendum]
Publicado: (2019)

Grape Seed Procyanidin B2 Protects Porcine Ovarian Granulosa Cells against Oxidative Stress-Induced Apoptosis by Upregulating let-7a Expression
por: Zhang, Jia-Qing, et al.
Publicado: (2019)

The effect of grape seed procyanidins extract on cognitive function in elderly people with mild cognitive impairment: A randomized, double-blind, placebo-controlled clinical trial
por: Li, Benchao, et al.
Publicado: (2023)

Potential Mitigation of Smoke Taint in Wines by Post-Harvest Ozone Treatment of Grapes
por: Modesti, Margherita, et al.
Publicado: (2021)

Impact of Commercial Oenotannin and Mannoprotein Products on the Chemical and Sensory Properties of Shiraz Wines Made from Sequentially Harvested Fruit
por: Li, Sijing, et al.
Publicado: (2018)

Reduction of G(0) phase cells of colon cancer caco-2 cells may enhance 5-fluorouracil efficacy()
por: Ye, Lin, et al.
Publicado: (2010)

Combined intravenous and intraperitoneal chemotherapy with fluorouracil + leucovorin vs fluorouracil + levamisole for adjuvant therapy of resected colon carcinoma.
por: Scheithauer, W., et al.
Publicado: (1998)

Anticancer Effect of Fluorouracil and Gum-Based Cerium Oxide Nanoparticles on Human Malignant Colon Carcinoma Cell Line (Caco(2))
por: Keramati, Zahra, et al.
Publicado: (2023)

Rhubarb extract partially improves mucosal integrity in chemotherapy-induced intestinal mucositis
por: Bajic, Juliana E, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_igencbdt4q10ou9hvua1s13332