Protective Effects of Astragaloside IV against Amyloid Beta1-42 Neurotoxicity by Inhibiting the Mitochondrial Permeability Transition Pore Opening

Mitochondrial dysfunction caused by amyloid β-peptide (Aβ) plays an important role in the pathogenesis of Alzheimer disease (AD). Substantial evidence has indicated that the mitochondrial permeability transition pore (mPTP) opening is involved in Aβ-induced neuronal death and reactive oxygen species...

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Detalles Bibliográficos
Autores principales: Sun, Qinru, Jia, Ning, Wang, Weixi, Jin, Hui, Xu, Jiehua, Hu, Haitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048237/
https://www.ncbi.nlm.nih.gov/pubmed/24905226
http://dx.doi.org/10.1371/journal.pone.0098866

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048237/
https://www.ncbi.nlm.nih.gov/pubmed/24905226
http://dx.doi.org/10.1371/journal.pone.0098866

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