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Associations of Filaggrin Gene Loss-of-Function Variants and Human Papillomavirus-Related Cancer and Pre-Cancer in Danish Adults

PURPOSE: Filaggrin proteins are expressed in the skin, oral cavity, oesophagus, and cervical mucose. Loss-of-function mutations in the filaggrin gene (FLG) reduce filaggrin expression and cause an impaired skin barrier function. We hypothesized that FLG mutation carriers would be more susceptible to...

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Detalles Bibliográficos
Autores principales: Skaaby, Tea, Husemoen, Lise Lotte N., Jørgensen, Torben, Johansen, Jeanne D., Menné, Torkil, Szecsi, Pal B., Stender, Steen, Bager, Peter, Thyssen, Jacob P., Linneberg, Allan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048243/
https://www.ncbi.nlm.nih.gov/pubmed/24905740
http://dx.doi.org/10.1371/journal.pone.0099437