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Trail Resistance Induces Epithelial-Mesenchymal Transition and Enhances Invasiveness by Suppressing PTEN via miR-221 in Breast Cancer

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) can selectively induce apoptosis of cancer cells and is verified effective to various cancers. However, a variety of breast cancer cell lines are resistant to TRAIL and the mechanisms of resistance are largely unknown. In our present ex...

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Detalles Bibliográficos
Autores principales: Wang, Haiji, Xu, Chunyuan, Kong, Xiaoli, Li, Xiaoyan, Kong, Xiangnan, Wang, Yu, Ding, Xia, Yang, Qifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048247/
https://www.ncbi.nlm.nih.gov/pubmed/24905916
http://dx.doi.org/10.1371/journal.pone.0099067